Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells

Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells

Abstract The ubiquitin-specific protease 22 (USP22) is an oncogene and its expression is upregulated in many types of cancer. In the nucleus, USP22 functions as one subunit of the SAGA to regulate gene transcription. However, the genome-wide USP22 binding sites and its direct target genes are yet cl...

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Bibliographic Details
Main Authors: Zhen Gong, Jianyun Liu, Xin Xie, Xiaoyuan Xu, Ping Wu, Huimin Li, Yaqin Wang, Weidong Li, Jianjun Xiong
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2018-06-01
Series:Genetics and Molecular Biology
Subjects:
USP22
target genes
ChIP-seq
knockdown
RNA-seq
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018005011101&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018005011101&lng=en&tlng=en

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