LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway

LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway

Abstract Background Adriamycin (ADR) resistance is one of the main obstacles to improving the clinical prognosis of breast cancer patients. Long noncoding RNAs (lncRNAs) can regulate cell behavior, but the role of these RNAs in the anti-ADR activity of breast cancer remains unclear. Here, we aim to...

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Bibliographic Details
Main Authors: Ming Zhang, Yan Wang, Longyang Jiang, Xinyue Song, Ang Zheng, Hua Gao, Minjie Wei, Lin Zhao
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Chemoresistance
Breast cancer
CBR3-AS1
miR-25-3p
MAPK signaling pathway
Online Access:https://doi.org/10.1186/s13046-021-01844-7

Internet

https://doi.org/10.1186/s13046-021-01844-7

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