Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset
Visceral leishmaniasis (VL) is a chronic and fatal disease caused by Leishmania infantum in Brazil. Leukocyte recruitment to infected tissue is a crucial event for the control of infections such as VL. Leucotriens are lipid mediators synthesized by 5-lipoxygenase (5-LO) and they display a protective...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2014/264270 |