Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset

Visceral leishmaniasis (VL) is a chronic and fatal disease caused by Leishmania infantum in Brazil. Leukocyte recruitment to infected tissue is a crucial event for the control of infections such as VL. Leucotriens are lipid mediators synthesized by 5-lipoxygenase (5-LO) and they display a protective...

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Bibliographic Details
Main Authors: Laís Amorim Sacramento, Fernando Q. Cunha, Roque Pacheco de Almeida, João Santana da Silva, Vanessa Carregaro
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/264270