Molecular Docking Study and Toxicity Risk Assessment of Some Novel Benzimidazole Oxime Ether Derivatives as CYP51 Inhibitors
Introduction: The azole class of compounds is the most popular among the antifungal classes because of its lower toxicity, higher efficacy, and a broad spectrum of activity. Ergosterol is the main component of the fungal cell membrane. Inhibition of the 14α-demethylase enzyme will result in decrease...
| Main Authors: | , |
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| Format: | Article |
| Language: | fas |
| Published: |
Ilam University of Medical Sciences
2019-03-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
| Subjects: | |
| Online Access: | http://sjimu.medilam.ac.ir/browse.php?a_code=A-10-4258-1&slc_lang=en&sid=1 |