Homology Modeling Study of Bovine μ-Calpain Inhibitor-Binding Domains

The activated mammalian CAPN-structures, the CAPN/CAST complex in particular, have become an invaluable target model using the structure-based virtual screening of drug candidates from the discovery phase to development for over-activated CAPN linked to several diseases, such as post-ischemic injury...

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Bibliographic Details
Main Authors: Han-Ha Chai, Dajeong Lim, Seung-Hwan Lee, Hee-Yeoul Chai, Eunkyoung Jung
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/5/7897