Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

Cancer is a clonal evolutionary process, caused by successive accumulation of genetic alterations providing milestones of tumor initiation, progression, dissemination, and/or resistance to certain therapeutic regimes. To unravel these milestones we propose a framework, tumor evolutionary directed gr...

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Bibliographic Details
Main Authors: Jiguang Wang, Hossein Khiabanian, Davide Rossi, Giulia Fabbri, Valter Gattei, Francesco Forconi, Luca Laurenti, Roberto Marasca, Giovanni Del Poeta, Robin Foà, Laura Pasqualucci, Gianluca Gaidano, Raul Rabadan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
tumor evolutionary
chronic lymphocytic leukemia
next generation sequencing
Online Access:https://elifesciences.org/articles/02869

Internet

https://elifesciences.org/articles/02869

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