Platelet activating factor contributes to vascular leak in acute dengue infection.

BACKGROUND:Although plasma leakage is the hallmark of severe dengue infections, the factors that cause increased vascular permeability have not been identified. As platelet activating factor (PAF) is associated with an increase in vascular permeability in other diseases, we set out to investigate it...

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Bibliographic Details
Main Authors: Chandima Jeewandara, Laksiri Gomes, N Wickramasinghe, Danuta Gutowska-Owsiak, Dominic Waithe, S A Paranavitane, N L A Shyamali, Graham S Ogg, Gathsaurie Neelika Malavige
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4315531?pdf=render