Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells

Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells

Abstract Background The thymus is a highly specialized organ of the immune system where T cell precursors develop and differentiate into self-tolerant CD4+ or CD8+ T cells. No studies to date have investigated how the human transcriptome profiles differ, between T cells still residing in the thymus...

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Bibliographic Details
Main Authors: Hanna Helgeland, Ingvild Gabrielsen, Helle Akselsen, Arvind Y. M. Sundaram, Siri Tennebø Flåm, Benedicte Alexandra Lie
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Genomics
Subjects:
RNA-seq
Transcriptome
Human
Thymus
T cells
Online Access:http://link.springer.com/article/10.1186/s12864-020-6755-1

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http://link.springer.com/article/10.1186/s12864-020-6755-1

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