Meta-Alignment with Crumble and Prune: Partitioning very large alignment problems for performance and parallelization

<p>Abstract</p> <p>Background</p> <p>Continuing research into the global multiple sequence alignment problem has resulted in more sophisticated and principled alignment methods. Unfortunately these new algorithms often require large amounts of time and memory to run, ma...

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Bibliographic Details
Main Authors: Paten Benedict, Roskin Krishna M, Haussler David
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/144