A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila

SUMMARY Insulin-resistant, ‘type 2’ diabetes (T2D) results from a complex interplay between genes and environment. In particular, both caloric excess and obesity are strongly associated with T2D across many genetic backgrounds. To gain insights into how dietary excess affects insulin resistance, we...

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Bibliographic Details
Main Authors: Laura Palanker Musselman, Jill L. Fink, Kirk Narzinski, Prasanna Venkatesh Ramachandran, Sumitha Sukumar Hathiramani, Ross L. Cagan, Thomas J. Baranski
Format: Article
Language:English
Published: The Company of Biologists 2011-11-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/6/842