CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8+ T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication

CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8+ T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication

Antigen-specific stem-like memory CD8+ T cells (Tscm) have a series of stem cell characteristics, including long-term survival, self-renewal, anti-apoptosis and persistent differentiation into cytotoxic T cells. The effective induction of tumor-specific CD8+ Tscm could persistently eradicate tumor i...

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Bibliographic Details
Main Authors: Yanmei Zhang, Nisha Wang, Meilin Ding, Yang Yang, Zhimin Wang, Lei Huang, Wei Zhu, Andrew L. Mellor, Xiaorui Hou, Chenfei Zhou, Ruiming Yan, Wei Wang, Sha Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Tscm
CD40
HPV
Wnt/β-catenin
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01012/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01012/full

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