Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner.

The transcription factors Runx1 and c-Myc have individually been shown to regulate important gene targets as well as to collaborate in oncogenesis. However, it is unknown whether there is a regulatory relationship between the two genes. In this study, we investigated the transcriptional regulation o...

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Bibliographic Details
Main Authors: Paejonette T Jacobs, Li Cao, Jeremy B Samon, Christyne A Kane, Emmett E Hedblom, Anne Bowcock, Janice C Telfer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715461?pdf=render