Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate

<p>Abstract</p> <p>Background</p> <p>Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers. Modelling the interactions betwee...

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Bibliographic Details
Main Authors: Khosravi Ebrahim, Du Tianchuan, Bai Shuju
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Bioinformatics