Tetraspanin 8-Rictor-Integrin α3 Complex Is Required for Glioma Cell Migration

Tetraspanin 8-Rictor-Integrin α3 Complex Is Required for Glioma Cell Migration

The malignant glioma remains one of the most aggressive human malignancies with extremely poor prognosis. Glioma cell invasion and migration are the main causes of death. In the current study, we studied the expression and the potential functions of tetraspanin 8 (Tspan8) in malignant gliomas. We fo...

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Bibliographic Details
Main Authors: Si-Jian Pan, Shi-Kun Zhan, Yi-Xin Pan, Wei Liu, Liu-Guan Bian, Bomin Sun, Qing-Fang Sun
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
malignant glioma
tetraspanin 8
integrin α3
rictor
mTORC2
AKT and cell migration
Online Access:http://www.mdpi.com/1422-0067/16/3/5363

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http://www.mdpi.com/1422-0067/16/3/5363

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