KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

Abstract Background KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved in bladder cancer progression remains unknown. Methods Tissue specimens were used to determine the expression levels and prognostic va...

Full description

Bibliographic Details
Main Authors: Lei Liu, Jianfeng Cui, Yajing Zhao, Xiaochen Liu, Lipeng Chen, Yangyang Xia, Yong Wang, Shouzhen Chen, Shuna Sun, Benkang Shi, Yongxin Zou
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Molecular Cancer
Subjects:
Bladder cancer
Metastasis
Epigenetics
KDM6A
ARHGDIB-Rac1 axis
FOXA1
Online Access:https://doi.org/10.1186/s12943-021-01369-9

Internet

https://doi.org/10.1186/s12943-021-01369-9

Similar Items