The combined role of allelic variants of IRS-1 and IRS-2 genes in susceptibility to type2 diabetes in the Punjabi Pakistani subjects

Abstract Background Diabetes mellitus is a multifactorial disorder characterized by a high level of glucose in the blood. Both genetic and environmental factors interact to cause diabetes. Insulin receptor substrate (IRS) proteins have a significant part in insulin signaling pathways. We aimed to in...

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Bibliographic Details
Main Authors: Anam Ijaz, Sana Babar, Sumbal Sarwar, Saleem Ullah Shahid, Shabana
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13098-019-0459-1