Synthesis and pharmacological screening of 4, 6-substituted di-(phenyl) pyrimidin-2-amines

A new series of 4, 6-substituted di-(phenyl) pyrimidin-2-amine (IIa–d) were synthesized by reacting chalcone derivatives with guanidine hydrochloride in the presence of dimethylformamide. The synthesized compounds were characterized by spectral analysis and were screened for anti-inflammatory activi...

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Bibliographic Details
Main Authors: Nitin Kumar, Sushma Drabu, Kumari Shalini
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212003140