The Major Cat Allergen Fel d 1 Binds Steroid and Fatty Acid Semiochemicals: A Combined In Silico and In Vitro Study

The Major Cat Allergen Fel d 1 Binds Steroid and Fatty Acid Semiochemicals: A Combined In Silico and In Vitro Study

The major cat allergen Fel d 1 is a tetrameric glycoprotein of the secretoglobin superfamily. Structural aspects and allergenic properties of this protein have been investigated, but its physiological function remains unclear. Fel d 1 is assumed to bind lipids and steroids like the mouse androgen-bi...

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Bibliographic Details
Main Authors: Cécile Bienboire-Frosini, Rajesh Durairaj, Paolo Pelosi, Patrick Pageat
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
secretoglobin
odorant-binding protein
chemical communication
pheromone
n-phenyl-1-naphthylamine
in silico docking
molecular modeling
protein–ligand interactions
2d interaction maps
ligand-binding assays
Online Access:https://www.mdpi.com/1422-0067/21/4/1365

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https://www.mdpi.com/1422-0067/21/4/1365

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