Fyn mediates leptin actions in the thymus of rodents.

BACKGROUND:Several effects of leptin in the immune system rely on its capacity to modulate cytokine expression and apoptosis in the thymus. Surprisingly, some of these effects are dependent on signal transduction through the IRS1/PI3-kinase, but not on the activation of JAK2. Since all the well know...

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Bibliographic Details
Main Authors: Alessandra Girasol, Gabriela G Albuquerque, Eli Mansour, Eliana P Araújo, Giovanna Degasperi, Raphael G Denis, José B Carvalheira, Mário J Saad, Lício A Velloso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2766049?pdf=render