The impact of sitagliptin on macrophage polarity and angiogenesis in the osteointegration of titanium implants in type 2 diabetes

Background: Clinical evidence indicates that sitagliptin treatment improves bone quality in diabetic patients, but the mechanisms involved remain elusive. Here, we studied the role of angiogenesis with sitagliptin treatment in diabetes-induced poor osteointegration of titanium implants and the under...

Full description

Bibliographic Details
Main Authors: Geng Xiang, Xinyi Huang, Tianji Wang, Jing Wang, Guoxuan Zhao, Han Wang, Yafei Feng, Wei Lei, Xiaofan Hu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220302699