Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

Among 15 nonstructural proteins (Nsps), the newly emerging Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) encodes a large, multidomain Nsp3. One of its units is the ADP-ribose phosphatase domain (ADRP; also known as the macrodomain, MacroD), which is believed to interfere with the host...

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Bibliographic Details
Main Authors: Karolina Michalska, Youngchang Kim, Robert Jedrzejczak, Natalia I. Maltseva, Lucy Stols, Michael Endres, Andrzej Joachimiak
Format: Article
Language:English
Published: International Union of Crystallography 2020-09-01
Series:IUCrJ
Subjects:
sars-cov-2
covid-19
macrodomain
adp-ribose phosphatase domain
adrp
nsp3
mac1
crystal structure
adp-ribosylation
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252520009653

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http://scripts.iucr.org/cgi-bin/paper?S2052252520009653

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