Into the Fourth Dimension: Dysregulation of Genome Architecture in Aging and Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by synapse dysfunction and cognitive impairment. Understanding the development and progression of AD is challenging, as the disease is highly complex and multifactorial. Both environmental and genetic factors play a ro...

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Bibliographic Details
Main Authors: Warren Winick-Ng, R. Jane Rylett
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00060/full