Role of Lipid Accumulation and Inflammation in Atherosclerosis: Focus on Molecular and Cellular Mechanisms

Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways that control the inflammation. This article reviews the role of inflammation and lipid accumulation, especially low-de...

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Bibliographic Details
Main Authors: Khojasteh Malekmohammad, Evgeny E. Bezsonov, Mahmoud Rafieian-Kopaei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
LDL
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.707529/full