SMYD2 promotes tumorigenesis and metastasis of lung adenocarcinoma through RPS7

Abstract The protein methyltransferase SET and MYND domain-containing protein 2 (SMYD2) is a transcriptional regulator that methylates histones and nonhistone proteins. As an oncogene, SMYD2 has been investigated in numerous types of cancer. However, its involvement in lung cancer remains elusive. T...

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Bibliographic Details
Main Authors: Lei Wu, Fan Kou, Zhenyu Ji, Baihui Li, Bailu Zhang, Yan Guo, Lili Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03720-w