Blood donor variability is a modulatory factor for P. falciparum invasion phenotyping assays

Abstract Human erythrocytes are indispensable for Plasmodium falciparum development. Unlike other eukaryotic cells, there is no existing erythroid cell line capable of supporting long-term P. falciparum in vitro experiments. Consequently, invasion phenotyping experiments rely on erythrocytes of diff...

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Bibliographic Details
Main Authors: Laty G. Thiam, Prince B. Nyarko, Kwadwo A. Kusi, Makhtar Niang, Yaw Aniweh, Gordon A. Awandare
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86438-1