Bauhinia championii Flavone Attenuates Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes by Improving Mitochondrial Dysfunction

Bauhinia championii Flavone Attenuates Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes by Improving Mitochondrial Dysfunction

This study aimed to determine the effects of Bauhinia championii flavone (BCF) on hypoxia-reoxygenation (H/R) induced apoptosis in H9c2 cardiomyocytes and to explore potential mechanisms. The H/R model in H9c2 cardiomyocytes was established by 6 h of hypoxia and 12 h of reoxygenation. Cell viability...

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Bibliographic Details
Main Authors: Ping Liao, Guibo Sun, Chan Zhang, Min Wang, Yao Sun, Yuehan Zhou, Xiaobo Sun, Jie Jian
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
Bauhinia championii flavone
hypoxia-reoxygenation
apoptosis
mitochondrial dysfunction
PI3K/Akt
Online Access:http://www.mdpi.com/1420-3049/21/11/1469

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http://www.mdpi.com/1420-3049/21/11/1469

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