Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning

Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning

The role of neurotrophic factors as endogenous survival proteins for brain neurons remains contentious. In the cerebellum, the signals controlling survival of molecular layer interneurons (MLIs) are unknown, and direct evidence for the requirement of a full complement of MLIs for normal cerebellar f...

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Bibliographic Details
Main Authors: Maria Christina Sergaki, Juan Carlos López-Ramos, Stefanos Stagkourakis, Agnès Gruart, Christian Broberger, José María Delgado-García, Carlos F. Ibáñez
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
cerebellum
eyeblink conditioning
neuronal migration
Purkinje cell
synaptic inhibition
vestibulo-ocular reflex
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717306721

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http://www.sciencedirect.com/science/article/pii/S2211124717306721

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