Chronic Nicotine Exposure Abolishes Maternal Systemic and Renal Adaptations to Pregnancy in Rats.

Chronic Nicotine Exposure Abolishes Maternal Systemic and Renal Adaptations to Pregnancy in Rats.

Pregnancy is characterized by maternal systemic and intrarenal vasodilation, leading to increases in the renal plasma flow (RPF) and glomerular filtration rate (GFR). These responses are mainly mediated by nitric oxide (NO) and relaxin. The impact of cigarette smoking on the maternal adaptations to...

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Bibliographic Details
Main Authors: Vanessa Meira Ferreira, Clevia Santos Passos, Edgar Maquigussa, Roberto Braz Pontes, Cassia Toledo Bergamaschi, Ruy Ribeiro Campos, Mirian Aparecida Boim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4768004?pdf=render

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http://europepmc.org/articles/PMC4768004?pdf=render

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