Immune response to combination therapy for non-Hodgkin lymphomas.

A parametric model of tumor response to combination therapy in the presence of an immune system is described. Synergistic mechanisms which induce tumor regression are simulated with a coupled set of equations. The simulations are first compared to tumor history data obtained with a SCID mouse model...

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Bibliographic Details
Main Authors: Robert F Weiss, Merlin G Miller, John F Cronin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855741?pdf=render