Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation.

Several successful pathogens have evolved mechanisms to evade host defense, resulting in the establishment of persistent and chronic infections. One such pathogen, Porphyromonas gingivalis, induces chronic low-grade inflammation associated with local inflammatory bone loss and systemic inflammation...

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Bibliographic Details
Main Authors: Connie Slocum, Stephen R Coats, Ning Hua, Carolyn Kramer, George Papadopoulos, Ellen O Weinberg, Cynthia V Gudino, James A Hamilton, Richard P Darveau, Caroline A Genco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4092147?pdf=render