Machine Learning From Molecular Dynamics Trajectories to Predict Caspase-8 Inhibitors Against Alzheimer’s Disease

Machine Learning From Molecular Dynamics Trajectories to Predict Caspase-8 Inhibitors Against Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder in which the death of brain cells takes place leading to loss of memory and decreased cognitive ability. AD is a leading cause of death worldwide and is progressive in nature with symptoms worsening over time. Machine learning–based computatio...

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Bibliographic Details
Main Authors: Salma Jamal, Abhinav Grover, Sonam Grover
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s
caspase-8
machine learning
molecular dynamics trajectories
descriptors
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00780/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00780/full

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