Moderate plasma dilution using artificial plasma expanders shifts the haemostatic balance to hypercoagulation

Abstract Artificial plasma expanders (PEs) are widely used in modern transfusion medicine. PEs do not contain components of the coagulation system, so their infusion in large volumes causes haemodilution and affects haemostasis. However, the existing information on this effect is contradictory. We s...

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Bibliographic Details
Main Authors: Elena I. Sinauridze, Alexander S. Gorbatenko, Elena A. Seregina, Elena N. Lipets, Fazoil I. Ataullakhanov
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00927-w