Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study.

BACKGROUND AND OBJECTIVES:Although the burden of non-alcoholic fatty liver disease (NAFLD) continues to increase worldwide, genetic factors predicting progression to cirrhosis and decompensation in NAFLD remain poorly understood. We sought to determine whether gene expression profiling was associate...

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Bibliographic Details
Main Authors: Kara Wegermann, Ricardo Henao, Anna Mae Diehl, Susan K Murphy, Manal F Abdelmalek, Cynthia A Moylan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6161885?pdf=render