Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates

Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates

Abstract Background Leptin plays an important role in mediating chondrogenesis of limb growth plate. Previous studies suggest that bone structures and development of spine and limb are different. The expression of Ob-Rb, the gene that encodes leptin receptors, is vertebral and appendicular region-sp...

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Bibliographic Details
Main Authors: Bo Yu, Kaibiao Jiang, Bin Chen, Hantao Wang, Xinfeng Li, Zude Liu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Leptin
Chondrogenesis
Vertebral growth plate
Tibial growth plate
Primary cell culture
Chondrocyte
Online Access:http://link.springer.com/article/10.1186/s12891-017-1601-6

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http://link.springer.com/article/10.1186/s12891-017-1601-6

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