Construction of <it>Bordetella pertussis </it>strains with enhanced production of genetically-inactivated Pertussis Toxin and Pertactin by unmarked allelic exchange
<p>Abstract</p> <p>Background</p> <p>Acellular Pertussis vaccines against whooping cough caused by <it>Bordetella pertussis </it>present a much-improved safety profile compared to the original vaccine of killed whole cells. The principal antigen of acellular...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-04-01
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| Series: | BMC Microbiology |
| Online Access: | http://www.biomedcentral.com/1471-2180/12/61 |