Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction1[S]

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction1[S]

Mammalian kidneys are rich in sulfatides. Papillary sulfatides, especially, contribute to renal adaptation to chronic metabolic acidosis. Due to differences in their cer­amide (Cer) anchors, the structural diversity of renal sulfatides is large. However, the underling biological function of this com...

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Bibliographic Details
Main Authors: Christian Marsching, Mariona Rabionet, Daniel Mathow, Richard Jennemann, Christiane Kremser, Stefan Porubsky, Christian Bolenz, Klaus Willecke, Hermann-Josef Gröne, Carsten Hopf, Roger Sandhoff
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Lipid Research
Subjects:
ceramide synthase 2
imaging mass spectrometry
liquid chromatography
matrix-assisted laser desorption/ionization-time-of-flight
electrospray ionization-mass spectrometry
tandem mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349877

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http://www.sciencedirect.com/science/article/pii/S0022227520349877

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