TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine that regulate...

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Bibliographic Details
Main Authors: Kana Tominaga, Hiroshi I. Suzuki
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/20/5002