Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

<p>Abstract</p> <p>Background</p> <p>Minocycline, a semi-synthetic tetracycline antibiotic, is an effective neuroprotective agent in animal models of cerebral ischemia when given in high doses intraperitoneally. The aim of this study was to determine if minocycline was...

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Bibliographic Details
Main Authors: Zheng Jianqing, Borlongan Cesar V, Edwards David, Waller Jennifer L, Fagan Susan C, Xu Lin, Hill William D, Feuerstein Giora, Hess David C
Format: Article
Language:English
Published: BMC 2004-04-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/4/7