Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors.

BACKGROUND: MicroRNAs (miRNAs) are reportedly involved in pancreatic ductal adenocarcinoma (PDAC) development. Current methods do not allow us to reliably monitor miRNA function. Asensors are adeno-associated virus (AAV) vector miRNA sensors for real-time consecutive functional monitoring of miRNA p...

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Bibliographic Details
Main Authors: Jing Chen, Xinjuan Liu, Xue Chen, Zihao Guo, Juan Liu, Jianyu Hao, Jie Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679063?pdf=render