Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia

Anoikis, a cell death mechanism triggered upon cell-matrix detachment, is regarded as a physiological suppressor of metastasis that can be regulated by a diverse array of signals. The protein encoded by GDF2 is BMP9 and is a member of the bone morphogenetic protein family and the transforming growth...

Full description

Bibliographic Details
Main Authors: Archana Varadaraj, Pratik Patel, Anne Serrao, Tirthankar Bandyopadhay, Nam Y. Lee, Amir A. Jazaeri, Zhiqing Huang, Susan K. Murphy, Karthikeyan Mythreye
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615001402