Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

Colinear HOX expression during hindbrain and spinal cord development diversifies and assigns regional neural phenotypes to discrete rhombomeric and vertebral domains. Despite the precision of HOX patterning in vivo, in vitro approaches for differentiating human pluripotent stem cells (hPSCs) to post...

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Bibliographic Details
Main Authors: Ethan S. Lippmann, Clay E. Williams, David A. Ruhl, Maria C. Estevez-Silva, Edwin R. Chapman, Joshua J. Coon, Randolph S. Ashton
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000740

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http://www.sciencedirect.com/science/article/pii/S2213671115000740

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