Engineering a Vascularized Hypoxic Tumor Model for Therapeutic Assessment

Solid tumors in advanced cancer often feature a structurally and functionally abnormal vasculature through tumor angiogenesis, which contributes to cancer progression, metastasis, and therapeutic resistances. Hypoxia is considered a major driver of angiogenesis in tumor microenvironments. However, t...

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Bibliographic Details
Main Authors: Yuta Ando, Jeong Min Oh, Winfield Zhao, Madeleine Tran, Keyue Shen
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/9/2201