Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.

PURPOSE:The lung is one of the most common sites of breast cancer metastasis. While metastatic seeding is often accompanied by a dormancy-promoting mesenchymal to epithelial reverting transitions (MErT), we aimed to determine whether lung epithelial cells can impart this phenotype on aggressive brea...

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Bibliographic Details
Main Authors: Masashi Furukawa, Sarah Wheeler, Amanda M Clark, Alan Wells
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4311980?pdf=render