Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel

Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel

Abstract.: Mechanisms for the atria-specific action potential-prolonging action of NIP-142 ((3R*,4S*)-4-cyclopropylamino-3,4-dihydro-2,2-dimethyl-6-(4-methoxyphenylacetylamino)-7-nitro-2H-1-benzopyran-3-ol), a benzopyran compound that terminates experimental atrial arrhythmia, was examined. In isola...

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Main Authors: Matsuda Tomoyuki, Ito Mie, Ishimaru Sayoko, Tsuruoka Noriko, Saito Tomoaki, Iida-Tanaka Naoko, Hashimoto Norio, Yamashita Toru, Tsuruzoe Nobutomo, Tanaka Hikaru, Shigenobu Koki
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344342

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http://www.sciencedirect.com/science/article/pii/S1347861319344342

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