1-Deoxynojirimycin Alleviates Liver Injury and Improves Hepatic Glucose Metabolism in db/db Mice

1-Deoxynojirimycin Alleviates Liver Injury and Improves Hepatic Glucose Metabolism in db/db Mice

The present study investigated the effect of 1-Deoxynojirimycin (DNJ) on liver injury and hepatic glucose metabolism in db/db mice. Mice were divided into five groups: normal control, db/db control, DNJ-20 (DNJ 20 mg·kg−1·day−1), DNJ-40 (DNJ 40 mg·kg−1·day−1) and DNJ-80 (DNJ 80 mg·kg−1·day−1). All d...

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Bibliographic Details
Main Authors: Qingpu Liu, Xuan Li, Cunyu Li, Yunfeng Zheng, Fang Wang, Hongyang Li, Guoping Peng
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
1-Deoxynojirimycin
db/db mice
liver
lipid metabolism
hepatic glucose metabolism
hepatic glycogen
glucose metabolic enzymes
hepatic insulin sensitivity
PKB/GSK-3β
Online Access:http://www.mdpi.com/1420-3049/21/3/279

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http://www.mdpi.com/1420-3049/21/3/279

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