Detection of KRAS mutations of colorectal cancer with peptide-nucleic-acid-mediated real-time PCR clamping

Colorectal cancer (CRC) is the third most common cancer in the world and its disease-specific mortality is estimated to be approximately 33% in the developed world. KRAS mutations have been shown to predict response to anti-EGFR (epidermal growth factor receptor) targeted monoclonal antibody therapy...

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Bibliographic Details
Main Authors: Xihong Zhao, Chia-Chen Chang, Tsung-Liang Chuang, Chii-Wann Lin
Format: Article
Language:English
Published: Taylor & Francis Group 2016-11-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2016.1228479