Angiotensin II type 1 receptor blockade partially attenuates hypoxia-induced pulmonary hypertension in newborn piglets: relationship with the nitrergic system

Angiotensin II type 1 receptor blockade partially attenuates hypoxia-induced pulmonary hypertension in newborn piglets: relationship with the nitrergic system

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The objective of this study was to observe possible interactions between the renin-angiotensin and nitrergic systems in chronic hypoxia-induced pulmonary hypertension in newborn piglets. Thirteen chronically instrumented newborn piglets (6.3 ± 0.9 days; 2369 ± 491 g) were randomly assigned to receiv...

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Bibliographic Details
Main Authors: J.S. Camelo Jr., A.R. Martins, E. Rosa, S.G. Ramos, D. Hehre, E. Bancalari, C. Suguihara
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Newborn animals
Pulmonary hypertension
Angiotensin II
Angiotensin receptors
Hypoxia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000200012&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000200012&lng=en&tlng=en

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