Detection in whole blood of autoantibodies for the diagnosis of connective tissue diseases in near patient testing condition.

A novel technology, photonic ring immunoassay (PRI), for detecting 12 autoantibodies simultaneously in whole blood in less than 15 minutes was evaluated by comparing results from 235 clinically diagnosed patients with standard laboratory tests. The overall agreement was greater than 91% for 10 of th...

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Bibliographic Details
Main Authors: Makoto Miyara, Jean-Luc Charuel, Sasi Mudumba, Alice Wu, Pascale Ghillani-Dalbin, Zahir Amoura, Rufus W Burlingame, Lucile Musset
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6116987?pdf=render