I-<it>kappa</it>-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

I-<it>kappa</it>-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

<p>Abstract</p> <p>Background</p> <p>IKK-2 is an important regulator of the nuclear factor-κB (NF-κB) which has been implicated in survival, proliferation and apoptosis resistance of lymphoma cells. In this study, we investigated whether inhibition of IKK-2 impacts cell...

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Bibliographic Details
Main Authors: Al-Katib Ayad, Arnold Alan A, Aboukameel Amro, Sosin Angela, Smith Peter, Mohamed Anwar N, Beck Frances W, Mohammad Ramzi M
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/228

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