New targets for the treatment of follicular lymphoma

by Al-Katib Ayad, Dandawate Prasad, Padheye Subhash, Tageja Nishant, Mohammad Ramzi M
Published 2009-12-01

SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status

by Aboukameel Amro, Chen Ben, Azmi Asfar, Goustin Anton, Sun Yuan, Al-Katib Ayad M, Mohammad Ramzi M
Published 2009-02-01

Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-X_Land Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model

by Al-Katib Ayad, Wang Shaomeng, Yang Dajun, Chen Jianyong, Aboukameel Amro, Arnold Alan A, Mohammad Ramzi M
Published 2008-02-01

HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (<it>cis</it>-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-ce...

by Sosin Angela M, Burger Angelika M, Siddiqi Aisha, Abrams Judith, Mohammad Ramzi M, Al-Katib Ayad M
Published 2012-09-01

An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals

by Yang Dajun, Wu Sherwin, Sosin Angela, Aboukameel Amro, Azmi Asfar S, Wu Jack, Mohammad Ramzi M, Wang Shaomeng, Al-Katib Ayad M
Published 2009-12-01

I-<it>kappa</it>-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

by Al-Katib Ayad, Arnold Alan A, Aboukameel Amro, Sosin Angela, Smith Peter, Mohamed Anwar N, Beck Frances W, Mohammad Ramzi M
Published 2010-09-01